Article
V-Phaser 2: variant inference for viral populations.
BMC genomics - 3 Oct 2013
Yang Xiao, Charlebois Patrick, Macalalad Alex, Henn Matthew R, Zody Michael C
Abstract excerpt
BACKGROUND: Massively parallel sequencing offers the possibility of revolutionizing the study of viral populations by providing ultra deep sequencing (tens to hundreds of thousand fold coverage) of complete viral genomes. However, differentiation of true low frequency variants from sequencing errors remains challenging. RESULTS: We developed a software package, V-Phaser 2, for inferring intrahost diversity within...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.