Article

Fast and sensitive mapping of error-prone nanopore sequencing reads with GraphMap

2015-06-10

Abstract excerpt

Exploiting the power of nanopore sequencing requires the development of new bioinformatics approaches to deal with its specific error characteristics. We present the first nanopore read mapper (GraphMap) that uses a read-funneling paradigm to robustly handle variable error rates and fast graph traversal to align long reads with speed and very high precision (>95%). Evaluation on MinION sequencing datasets against...

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Literature Corpus work: 3330b0bf-f959-5994-9929-316a76593706
DOI: 10.1101/020719

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