Article
Fast and sensitive mapping of nanopore sequencing reads with GraphMap.
Nature communications - 15 Apr 2016
Sović Ivan, Šikić Mile, Wilm Andreas, Fenlon Shannon Nicole, Chen Swaine, Nagarajan Niranjan
Abstract excerpt
Realizing the democratic promise of nanopore sequencing requires the development of new bioinformatics approaches to deal with its specific error characteristics. Here we present GraphMap, a mapping algorithm designed to analyse nanopore sequencing reads, which progressively refines candidate alignments to robustly handle potentially high-error rates and a fast graph traversal to align long reads with speed and...
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