Article
Detection of viral pathogens with multiplex Nanopore MinION sequencing: be careful with cross-talk
2018-04-25
Abstract excerpt
Metagenomic sequencing with the Oxford Nanopore MinION sequencer offers potential for point-of-care testing of infectious diseases in clinical settings. To improve cost-effectiveness, multiplexing of several, barcoded samples upon a single flow cell will be required during sequencing. We generated a unique sequencing dataset to assess the extent and source of cross barcode contamination caused by multiplex MinION...
Topics
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- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Infective Endocarditis Diagnosis and Management
- Influenza Virus Research Studies
- Insect symbiosis and bacterial influences
- Mosquito-borne diseases and control
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- 73379a0f-81e1-52a9-81c7-94df36513db3
- DOI
- 10.1101/308262
