Article
Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults.
British journal of clinical pharmacology - 1 Feb 2020
Suenderhauf Claudia, Berger Benjamin, Puchkov Maxim, Schmid Yasmin, Müller Sabine, Huwyler Jörg, Haschke Manuel, Krähenbühl Stephan, Duthaler Urs
Abstract excerpt
AIMS: We compared the phenotyping metrics of a combination capsule formulation to its individual components of the newly composed Basel phenotyping cocktail. Moreover, we investigated a reduced sampling regimen for clinical applications. METHODS: We performed in vitro experiments and a crossover pharmacokinetic study in twelve healthy male subjects to compare the Basel phenotyping cocktail capsule containing 6...
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