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Article

The basel cocktail for simultaneous phenotyping of human cytochrome P450 isoforms in plasma, saliva and dried blood spots.

Clinical pharmacokinetics - 1 Mar 2014

Donzelli Massimiliano, Derungs Adrian, Serratore Maria-Giovanna, Noppen Christoph, Nezic Lana, Krähenbühl Stephan, Haschke Manuel

Abstract excerpt

BACKGROUND AND OBJECTIVE: Phenotyping cocktails use a combination of cytochrome P450 (CYP)-specific probe drugs to simultaneously assess the activity of different CYP isoforms. To improve the clinical applicability of CYP phenotyping, the main objectives of this study were to develop a new cocktail based on probe drugs that are widely used in clinical practice and to test whether alternative sampling methods such...

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Identifiers

PMID: 24218006
DOI: 10.1007/s40262-013-0115-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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