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A Genome-Wide Screen for Wortmannin-Resistant Mutants in Schizosaccharomyces pombe: The Phosphorylation-Impaired Mutants Are Resistant to Signaling Defect.

DNA and cell biology - 1 Dec 2019

Yılmazer Merve, Kartal Burcu, Tarhan Çağatay, Özarabacı Ilayda, Akçaalan Sedef, Özkan Egemen, Karaer Uzuner Semian, Arıcan Ercan, Palabıyık Bedia

Abstract excerpt

Complex human diseases such as metabolic disorders, cancer, neurodegenerative diseases, and mitochondrial dysfunctions arise from the biochemical or genetic defects in various cellular processes. Therefore, it is important to understand which metabolic processes are affected by which cellular impairment. Because genome-wide screening of mutant collections (haploid/diploid deletion library) provides important...

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PMID: 31657618
DOI: 10.1089/dna.2019.5003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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