Article

Towards a systematic map of the functional role of protein phosphorylation

2019-12-11

Abstract excerpt

Phosphorylation is a critical post-translational modification involved in the regulation of almost all cellular processes. However, less than 5% of thousands of recently discovered phosphorylation sites have a known function. Here, we devised a chemical genetic approach to study the functional relevance of phosphorylation in S. cerevisiae . We generated 474 phospho-deficient mutants that, along with the gene dele...

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Literature Corpus work: f3d3d1d1-5dff-5b1d-b2a6-aa23bf8ff618
DOI: 10.1101/872770

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