Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

1 Dec 2011

Abstract excerpt

TOR (Target Of Rapamycin) is a highly conserved protein kinase that is important in both fundamental and clinical biology. In fundamental biology, TOR is a nutrient-sensitive, central controller of cell growth and aging. In clinical biology, TOR is implicated in many diseases and is the target of the drug rapamycin used in three different therapeutic areas. The yeast Saccharomyces cerevisiae has played a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal and yeast genetics research
Share to Fungal Biology and Applications
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22174183
DOI: 10.1534/genetics.111.133363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Target of Rapamycin (TOR) in Nutrient Signaling and Growth ControlPMID 22174183Read ↗

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read ↗

Identification of TOR signaling complexes: more TORC for the cell growth engine.Semantic proximity Read ↗

TOR, the Gateway to Cellular Metabolism, Cell Growth, and DiseaseSemantic proximity Read ↗

Structure-based engineering of Tor complexes uncovers different roles of two types of yeast TORC1sSemantic proximity Read ↗

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in AgingSemantic proximity Read ↗

Who does TORC2 talk to?Semantic proximity Read ↗

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine.Semantic proximity Read ↗

The TOR signaling cascade regulates gene expression in response to nutrients.Semantic proximity Read ↗

mTOR Pathways in Cancer and AutophagySemantic proximity Read ↗

Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes.Semantic proximity Read ↗

Nuclear Functions of TOR: Impact on Transcription and the EpigenomeSemantic proximity Read ↗

mTOR signalling: jack-of-all-tradesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.