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Article

A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.

PloS one - 1 Jan 2013

Zhou Xin, Ma Yan, Fang Yue, gerile Wugan, Jaiseng Wurentuya, Yamada Yuki, Kuno Takayoshi

Abstract excerpt

Micafungin is a non-reversible inhibitor of 1, 3-β-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive candidiasis and invasive aspergillosis. However, considering its relatively restricted antifungal spectrum, combination therapy with micafungin plus other agents should be considered in critically ill patients. To...

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Identifiers

PMID: 23738021
DOI: 10.1371/journal.pone.0065904
PMCID: PMC3667807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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