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Article

Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.

Biochemical and biophysical research communications - 3 Dec 2024

Cipak Lubos, Sivakova Barbara, Bellova Jana, Danchenko Maksym, Jurcik Jan, Cipakova Ingrid, Lalakova Laura Olivia, Gregan Juraj, Barath Peter

Abstract excerpt

Ksg1 is an essential protein kinase of the fission yeast S. pombe that belongs to the AGC kinase family and is homologous to the mammalian PDPK1 kinase. Previous studies have shown that Ksg1 functions in the nutrient-sensing TOR signaling pathway and is involved in the phosphorylation and activation of other AGC kinases, thereby affecting various downstream targets related to metabolism, cell division, stress...

Topics

Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Phosphorylation
Proteome
Phosphoproteins
Protein Kinases
Signal Transduction
Proteomics
Mutation
Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39476757
DOI: 10.1016/j.bbrc.2024.150895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-39476757-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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