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Article

Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology

9 Aug 2019

Abstract excerpt

Abstract Introduction We sought biological pathways that explained discordance between Alzheimer's disease (AD) pathology and symptoms. Methods In 306 Alzheimer's Disease Neuroimaging Initiative (ADNI)‐1 participants across the AD clinical spectrum, we investigated association between cognitive outcomes and 23 cerebrospinal fluid (CSF) analytes associated with abnormalities in the AD biomarkers amyloid β1‐42 and...

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PMID: 31405825
DOI: 10.1016/j.jalz.2019.05.007

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