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Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics

9 Sept 2020

Abstract excerpt

Alzheimer's disease is biologically heterogeneous, and detailed understanding of the processes involved in patients is critical for development of treatments. CSF contains hundreds of proteins, with concentrations reflecting ongoing (patho)physiological processes. This provides the opportunity to study many biological processes at the same time in patients. We studied whether Alzheimer's disease biological...

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PMID: 33439986
DOI: 10.1093/brain/awaa325

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