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Aβ-related Cerebrospinal Fluid Proteins in Alzheimer’s Disease Reflect Gene Expression Levels Found in The Healthy Cortex

2026-03-08

Abstract excerpt

<title>Abstract</title> <p>A growing body of evidence indicates that CSF proteomic signatures shift with increasing brain amyloidosis in Alzheimer’s disease (AD). However, it remains unknown whether protein profiles within cortical regions that are vulnerable to early amyloid-beta (Aβ) deposition contribute to, or predict, CSF Aβ-related protein measures. To address this question, we examined 220 cognitively unim...

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Literature Corpus work
4fdba12d-f32a-5635-9d01-aa28c01a09a8
DOI
10.21203/rs.3.rs-8428920/v1
Open publication

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Aβ-related Cerebrospinal Fluid Proteins in Alzheimer’s Disease Reflect Gene Expression Levels Found in The Healthy CortexDOI 10.21203/rs.3.rs-8428920/v1
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