Article

Alzheimer’s disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression

2024-06-13

Abstract excerpt

<h4>INTRODUCTION</h4> Normal pressure hydrocephalus (NPH) patients undergoing cortical shunting frequently show early AD pathology on cortical biopsy, which is predictive of progression to clinical AD. The objective of this study was to use samples from this cohort to identify CSF biomarkers for AD-related CNS pathophysiologic changes using tissue and fluids with early pathology, free of post-mortem artifact. <h4>...

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Literature Corpus work: ccc03bd8-fe6d-5e4f-957e-c40676e1fe0a
DOI: 10.1101/2024.06.11.24308706

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