Article
Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.
Blood advances - 13 Aug 2019
Howie Heather L, Hay Ariel M, de Wolski Karen, Waterman Hayley, Lebedev Jenna, Fu Xiaoyun, Culp-Hill Rachel, D'Alessandro Angelo, Gorham James D, Ranson Matthew S, Roback John D, Thomson Peter C, Zimring James C
Abstract excerpt
Red blood cells (RBCs) are the most numerous cell type in the body and serve a vital purpose of delivering oxygen to essentially all tissues. In addition to the central role of RBCs in health and disease, RBC storage is a requirement for the >90 million units of RBC transfusions given to millions of recipients each year, worldwide. It is well known that there is genetic donor-to-donor variability in how human...
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