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Article

Type VI collagen promotes lung epithelial cell spreading and wound-closure.

PloS one - 1 Jan 2018

Mereness Jared A, Bhattacharya Soumyaroop, Wang Qian, Ren Yue, Pryhuber Gloria S, Mariani Thomas J

Abstract excerpt

Basement membrane (BM) is an essential part of the extracellular matrix (ECM) that plays a crucial role in mechanical support and signaling to epithelial cells during lung development, homeostasis and repair. Abnormal composition and remodeling of the lung ECM have been associated with developmental abnormalities observed in multiple pediatric and adult respiratory diseases. Collagen VI (COL6) is a well-studied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30550606
DOI: 10.1371/journal.pone.0209095
PMCID: PMC6294368

Genes

CDC42
RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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