Article
The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation.
Cells - 6 Jan 2022
Hackett Tillie-Louise, Vriesde Noamie R T F, Al-Fouadi May, Mostaco-Guidolin Leila, Maftoun Delaram, Hsieh Aileen, Coxson Nicole, Usman Kauna, Sin Don D, Booth Steve, Osei Emmanuel T
Abstract excerpt
The extracellular matrix (ECM) supports lung tissue architecture and physiology by providing mechanical stability and elastic recoil. Over the last several decades, it has become increasingly clear that the stiffness of the ECM governs many cellular processes, including cell-phenotype and functions during development, healing, and disease. Of all the lung ECM proteins, collagen-I is the most abundant and provides...
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