Article
The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture.
Biomaterials - 1 Oct 2011
Pageau Steven C, Sazonova Olga V, Wong Joyce Y, Soto Ana M, Sonnenschein Carlos
Abstract excerpt
The stroma plays an important role in the development and progression of human diseases. Pulmonary diseases such as asthma, fibrosis and cancer are thought to be the result of altered communications between the epithelial and stromal tissue compartments. In order to study these epithelial-mesenchymal interactions, we developed a three dimensional (3D) in vitro model of the human airway that mimics bronchial...
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