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A Genome-Wide Study of Allele-Specific Expression in Colorectal Cancer

27 Nov 2018

Abstract excerpt

Accumulating evidence from small-scale studies has suggested that allele-specific expression (ASE) plays an important role in tumor initiation and progression. However, little is known about genome-wide ASE in tumors. In this study, we conducted a comprehensive analysis of ASE in individuals with colorectal cancer (CRC) on a genome-wide scale. We identified 5.4 thousand genome-wide ASEs of single nucleotide...

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Identifiers

PMID: 30538721
DOI: 10.3389/fgene.2018.00570

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