Article
Large-scale profiling and identification of potential regulatory mechanisms for allelic gene expression in colorectal cancer cells.
Gene - 1 Jan 2013
Lee Robin Dong-Woo, Song Min-Young, Lee Jong-Keuk
Abstract excerpt
Allelic variation in gene expression is common in humans and this variation is associated with phenotypic variation. In this study, we employed high-density single nucleotide polymorphism (SNP) chips containing 13,900 exonic SNPs to identify genes with allelic gene expression in cells from colorectal cancer cell lines. We found 2 monoallelically expressed genes (ERAP2 and MYLK4), 32 genes with an allelic...
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