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Article

cisASE: a likelihood-based method for detecting putative cis-regulated allele-specific expression in RNA sequencing data.

Bioinformatics (Oxford, England) - 1 Nov 2016

Liu Zhi, Gui Tuantuan, Wang Zhen, Li Hong, Fu Yunhe, Dong Xiao, Li Yixue

Abstract excerpt

MOTIVATION: Allele-specific expression (ASE) is a useful way to identify cis-acting regulatory variation, which provides opportunities to develop new therapeutic strategies that activate beneficial alleles or silence mutated alleles at specific loci. However, multiple problems hinder the identification of ASE in next-generation sequencing (NGS) data. RESULTS: We developed cisASE, a likelihood-based method for...

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PMID: 27412088
DOI: 10.1093/bioinformatics/btw416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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