Article

IMPALA: A Comprehensive Pipeline for Detecting and Elucidating Mechanisms of Allele Specific Expression in Cancer

2023-09-12

Abstract excerpt

<h4>Summary</h4> Allele-specific expression (ASE), where transcripts from one allele are more abundant than transcripts from the other, can arise from various genetic mechanisms and has implications for gene regulation and disease. We present IMPALA (Integrated Mapping and Profiling of Allelically-expressed Loci with Annotations), a versioned and containerized pipeline for detecting ASE in samples including cance...

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Literature Corpus work: eb63f549-8eb8-58a6-976b-e7ebed71d0fe
DOI: 10.1101/2023.09.11.555771

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