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Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis

1 Dec 2018

Abstract excerpt

BACKGROUND: Dysfunction of the circadian clock and polymorphisms of some circadian genes have been linked to cancer development and progression. We investigated the relationship between circadian genes germline variation and susceptibility or prognosis of patients with soft tissue sarcoma. PATIENTS AND METHODS: We considered the 14 single nucleotide polymorphisms (SNPs) of 6 core circadian genes that have a minor...

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PMID: 30518396
DOI: 10.1186/s12967-018-1715-0

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