Article
Circadian pathway genes in relation to glioma risk and outcome.
Cancer causes & control : CCC - 1 Jan 2014
Madden Melissa H, Anic Gabriella M, Thompson Reid C, Nabors L Burton, Olson Jeffrey J, Browning James E, Monteiro Alvaro N, Egan Kathleen M
Abstract excerpt
PURPOSE: There is growing evidence that circadian disruption may alter risk and aggressiveness of cancer. We evaluated common genetic variants in the circadian gene pathway for associations with glioma risk and patient outcome in a US clinic-based case-control study. METHODS: Subjects were genotyped for 17 candidate single nucleotide polymorphisms in ARNTL, CRY1, CRY2, CSNK1E, KLHL30, NPAS2, PER1, PER3, CLOCK,...
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