Article
Circadian genes and breast cancer susceptibility in rotating shift workers.
International journal of cancer - 1 Dec 2012
Monsees Genevieve M, Kraft Peter, Hankinson Susan E, Hunter David J, Schernhammer Eva S
Abstract excerpt
Rotating night shift work is associated with increased risk of breast cancer, likely via circadian disruption. We hypothesized that circadian pathway genes influence breast cancer risk, particularly in rotating night shift workers. We selected 178 common variants across 15 genes pertinent to the...
Topics
- Adult
- Alleles
- Basic Helix-Loop-Helix Transcription Factors
- Breast Neoplasms
- Circadian Rhythm
- Cohort Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Middle Aged
- Nerve Tissue Proteins
- Polymorphism, Single Nucleotide
- Risk Factors
- White People
- Work
- Work Schedule Tolerance