Article
Circadian pathway genetic variation and cancer risk: evidence from genome-wide association studies.
BMC medicine - 19 Feb 2018
Mocellin Simone, Tropea Saveria, Benna Clara, Rossi Carlo Riccardo
Abstract excerpt
BACKGROUND: Dysfunction of the circadian clock and single polymorphisms of some circadian genes have been linked to cancer susceptibility, although data are scarce and findings inconsistent. We aimed to investigate the association between circadian pathway genetic variation and risk of developing common cancers based on the findings of genome-wide association studies (GWASs). METHODS: Single nucleotide...
Topics
- Circadian Clocks
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Neoplasms
- Polymorphism, Single Nucleotide
- Risk