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Article

Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.

Oncotarget - 4 Apr 2017

Benna Clara, Helfrich-Förster Charlotte, Rajendran Senthilkumar, Monticelli Halenya, Pilati Pierluigi, Nitti Donato, Mocellin Simone

Abstract excerpt

BACKGROUND: The number of studies on the association between clock genes' polymorphisms and cancer susceptibility has increased over the last years but the results are often conflicting and no comprehensive overview and quantitative summary of the evidence in this field is available. RESULTS: Literature search identified 27 eligible studies comprising 96756 subjects (cases: 38231) and investigating 687...

Topics

Adult
Circadian Clocks
Female
Genetic Variation
Humans
Neoplasms
Polymorphism, Single Nucleotide
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28177907
DOI: 10.18632/oncotarget.15074
PMCID: PMC5410358

Genes

CLOCK
NPAS2
PER3
RORA
RORB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28177907-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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