Article
Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma.
International journal of cancer - 15 Jan 2007
Zhu Yong, Leaderer Derek, Guss Carly, Brown Heather N, Zhang Yawei, Boyle Peter, Stevens Richard G, Hoffman Aaron, Qin Qin, Han Xuesong, Zheng Tongzhang
Abstract excerpt
Circadian disruption is theorized to cause immune dysregulation, which is the only established risk factor for non-Hodgkin's lymphoma (NHL). Genes responsible for circadian rhythm are also involved in cancer-related biological pathways as potential tumor suppressors. However, no previous studies have examined associations between circadian genes and NHL risk. In this population-based case control study (n = 455...
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