Breast cancer risk, nightwork, and circadian clock gene polymorphisms.

doi:10.1530/ERC-14-0121

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Article

Breast cancer risk, nightwork, and circadian clock gene polymorphisms.

Endocrine-related cancer - 1 Aug 2014

Truong Thérèse, Liquet Benoît, Menegaux Florence, Plancoulaine Sabine, Laurent-Puig Pierre, Mulot Claire, Cordina-Duverger Emilie, Sanchez Marie, Arveux Patrick, Kerbrat Pierre, Richardson Sylvia, Guénel Pascal

Abstract excerpt

Night shift work has been associated with an increased risk of breast cancer pointing to a role of circadian disruption. We investigated the role of circadian clock gene polymorphisms and their interaction with nightwork in breast cancer risk in a population-based case-control study in France including 1126 breast cancer cases and 1174 controls. We estimated breast cancer risk associated with each of the 577...

Topics

Adult
Aged
Basic Helix-Loop-Helix Transcription Factors
Breast Neoplasms
CLOCK Proteins
Case-Control Studies
Circadian Clocks
Female
France
Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Middle Aged

Nerve Tissue Proteins

Nuclear Receptor Subfamily 1, Group F, Member 1

Polymorphism, Single Nucleotide

Postmenopause

Risk

Work

Source

Open in PubMed

Identifiers

PMID: 24919398
DOI: 10.1530/ERC-14-0121

Genes

CLOCK
RORA
NPAS2
PER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24919398-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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