Article
nanoDSF as screening tool for enzyme libraries and biotechnology development.
The FEBS journal - 1 Jan 2019
Magnusson Anders O, Szekrenyi Anna, Joosten Henk-Jan, Finnigan James, Charnock Simon, Fessner Wolf-Dieter
Abstract excerpt
Enzymes are attractive tools for synthetic applications. To be viable for industrial use, enzymes need sufficient stability towards the desired reaction conditions such as high substrate and cosolvent concentration, non-neutral pH and elevated temperatures. Thermal stability is an attractive feature not only because it allows for protein purification by thermal treatment and higher process temperatures but also...
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