Article
Phage display selection of tight specific binding variants from a hyperthermostable Sso7d scaffold protein library.
The FEBS journal - 1 Apr 2016
Zhao Ning, Schmitt Margaret A, Fisk John D
Abstract excerpt
Antibodies, the quintessential biological recognition molecules, are not ideal for many applications because of their large size, complex modifications, and thermal and chemical instability. Identifying alternative scaffolds that may be evolved into tight, specific binding molecules with improved physical properties is of increasing interest, particularly for biomedical applications in resource-limited...
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