Understanding the basis of thermostability for enzyme "Nanoluc" towards designing industry-competent engineered variants.

Abstract excerpt

As a leading contender in the study of luminescence, nanoluciferase has recently attracted attention and proven effective in a wide variety of research areas. Although numerous attempts have been made to improve activity, there has yet to be a thorough exploration of further possibilities to improve thermostability. In this study, protein engineering in tandem with molecular dynamics simulation at various...

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