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Article

Protein engineering of a thermostable polyol dehydrogenase.

Enzyme and microbial technology - 10 Sept 2012

Wulf H, Mallin H, Bornscheuer U T

Abstract excerpt

The polyol dehydrogenase PDH-11300 from Deinococcus geothermalis was cloned, functionally expressed in Escherichia coli and biochemically characterized. The enzyme showed the highest activity in the oxidation of xylitol and 1,2-hexanediol and had an optimum temperature of 45 °C. The enzyme exhibited a T⁶⁰₅₀-value of 48.3 °C. The T⁶⁰₅₀ is the temperature where 50% of the initial activity remains after incubation...

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Identifiers

PMID: 22883556
DOI: 10.1016/j.enzmictec.2012.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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