Multi-strategy orthogonal enhancement and analysis of aldo-keto reductase thermal stability.

Abstract excerpt

Given their outstanding efficiency and selectivity, enzymes are integral in various domains such as drug synthesis, the food industry, and environmental management. However, the inherent instability of natural enzymes limits their widespread industrial application. In this study, we underscore the efficacy of enhancing protein thermal stability through comprehensive protein design strategies, encompassing...

Topics

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• Enzyme Stability
• Mutation
• Point Mutation
• Protein Stability
• Temperature