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Molecular Control of Follicular Helper T cell Development and Differentiation

25 Oct 2018

Abstract excerpt

Follicular helper T cells (Tfh) are specialized helper T cells that are predominantly located in germinal centers and provide help to B cells. The development and differentiation of Tfh cells has been shown to be regulated by transcription factors, such as B-cell lymphoma 6 protein (Bcl-6), signal transducer and activator of transcription 3 (STAT3) and B lymphocyte-induced maturation protein-1 (Blimp-1). In...

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PMID: 30410493
DOI: 10.3389/fimmu.2018.02470

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