Article
The elusive identity of T follicular helper cells.
Trends in immunology - 1 Oct 2010
Yu Di, Vinuesa Carola G
Abstract excerpt
Follicular helper T (Tfh) cells provide help to B cells and allow formation of long-lived antibody responses. Despite an improved understanding of the molecular program that drives Tfh cell formation, their definition remains elusive: neither follicular homing ability, Bcl-6 expression nor IL-21 secretion are exclusive properties of T cells that help B cells, and not all follicular T cells are B cell helpers....
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