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Article

Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors

1 Jan 2020

Abstract excerpt

T helper cells, which is specialized in helping B cells in the germinal center reaction. Tfh cells express high levels of CXCR5, PD-1, IL-21, and other characteristic markers. Accumulating evidence has demonstrated that the dysregulation of Tfh cells is involved in infectious, inflammatory, and autoimmune diseases, including lymphocytic choriomeningitis virus (LCMV) infection, inflammatory bowel disease (IBD),...

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PMID: 32766317
DOI: 10.1155/2020/1826587

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