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Article

Signals that drive T follicular helper cell formation.

Immunology - 1 Oct 2017

Webb Louise M C, Linterman Michelle A

Abstract excerpt

T follicular helper (Tfh) cells are a distinct type of CD4+ T cell specialized in providing help to B cells during the germinal centre (GC) reaction. As such, they are critical determinants of the quality of an antibody response following antigen challenge. Excessive production of Tfh cells can result in autoimmunity whereas too few can result in inadequate protection from infection. Hence, their differentiation...

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Share to Antibody Formation
Share to Antigens
Share to Germinal Center

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Cell Differentiation

Share to Receptors, Antigen, T-Cell

Share to Signal Transduction

Share to T-Lymphocytes, Helper-Inducer

Source

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Identifiers

PMID: 28628194
DOI: 10.1111/imm.12778
PMCID: PMC5588773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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