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Article

Current concepts and challenges to unravel the role of iodothyronine deiodinases in human neoplasias

5 Oct 2018

Abstract excerpt

Thyroid hormones (THs) are essential for the regulation of several metabolic processes and the energy consumption of the organism. Their action is exerted primarily through interaction with nuclear receptors controlling the transcription of thyroid hormone-responsive genes. Proper regulation of TH levels in different tissues is extremely important for the equilibrium between normal cellular proliferation and...

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PMID: 30400023
DOI: 10.1530/erc-18-0097

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