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Article

Pretranslational Regulation of Type 2 Deiodinase

1 Aug 2005

Abstract excerpt

Type 2 deiodinase (D2) is a highly potent selenoenzyme that catalyzes the first step of thyroid hormone action and its expression is under close, multilevel control. D2 expression is tissue specific and can be regulated by transcriptional and posttranscriptional mechanisms. There is now compelling evidence that D2 is critically important in triiodothyronine (T3) homeostasis as well as in several biologic...

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Identifiers

PMID: 16131328
DOI: 10.1089/thy.2005.15.855

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