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Article

Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells.

Archives of toxicology - 1 Jun 2013

Song Mee, Song Mi-Kyung, Choi Han-Seam, Ryu Jae-Chun

Abstract excerpt

Iodothyronine deiodinase types I, II, and III (D1, D2, and D3, respectively), which constitute a family of selenoenzymes, activate and inactivate thyroid hormones through the removal of specific iodine moieties from thyroxine and its derivatives. These enzymes are important in the biological effects mediated by thyroid hormones. The expression of activating and inactivating deiodinases plays a critical role in a...

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Source

Identifiers

PMID: 23397585
DOI: 10.1007/s00204-013-1018-4

Genes

CCL2
GULP1
ITGB5
KLF9
TBX3
TGOLN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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