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Article

Iodothyronine deiodinase structure and function: from ascidians to humans.

The Journal of endocrinology - 1 Nov 2012

Darras Veerle M, Van Herck Stijn L J

Abstract excerpt

Iodothyronine deiodinases are important mediators of thyroid hormone (TH) action. They are present in tissues throughout the body where they catalyse 3,5,3'-triiodothyronine (T(3)) production and degradation via, respectively, outer and inner ring deiodination. Three different types of iodothyronine deiodinases (D1, D2 and D3) have been identified in vertebrates from fish to mammals. They share several common...

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PMID: 22825922
DOI: 10.1530/JOE-12-0204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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