Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iodothyronine deiodinases: a functional and evolutionary perspective.

The Journal of endocrinology - 1 Nov 2012

Orozco Aurea, Valverde-R Carlos, Olvera Aurora, García-G Carlota

Abstract excerpt

From an evolutionary perspective, deiodinases may be considered pivotal players in the emergence and functional diversification of both thyroidal systems (TS) and their iodinated messengers. To better understand the evolutionary pathway and the concomitant functional diversification of vertebrate deiodinases, in the present review we summarized the highlights of the available information regarding this ubiquitous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Genetic Variation
Share to Iodide Peroxidase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phylogeny

Share to Thyroid Gland

Share to Tyrosine

Source

Identifiers

PMID: 22872760
DOI: 10.1530/JOE-12-0258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iodothyronine deiodinases: a functional and evolutionary perspective.PMID 22872760Read ↗

Iodothyronine deiodinase structure and function: from ascidians to humans.Semantic proximity Read ↗

Current concepts and challenges to unravel the role of iodothyronine deiodinases in human neoplasiasSemantic proximity Read ↗

The roles of the iodothyronine deiodinases in mammalian development.Semantic proximity Read ↗

Deiodinases and CancerSemantic proximity Read ↗

Type 3 deiodinase and solid tumors: an intriguing pairSemantic proximity Read ↗

Thyroid Hormone Deiodinases: Dynamic Switches in Developmental TransitionsSemantic proximity Read ↗

Biochemical mechanisms of thyroid hormone deiodination.Semantic proximity Read ↗

Pretranslational Regulation of Type 2 DeiodinaseSemantic proximity Read ↗

Permanent Deiodinase Type 2 Deficiency Strongly Perturbs Zebrafish Development, Growth, and Fertility.Semantic proximity Read ↗

Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences.Semantic proximity Read ↗

The Physiological Functions and Polymorphisms of Type II DeiodinaseSemantic proximity Read ↗

Towards the pre-clinical diagnosis of hypothyroidism caused by iodotyrosine deiodinase (DEHAL1) defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.