Article

Thyroid Hormone, Cancer, and Apoptosis

2016-07-01

Abstract excerpt

ABSTRACT Thyroid hormones play important roles in regulating normal metabolism, development, and growth. They also stimulate cancer cell proliferation. Their metabolic and developmental effects and growth effects in normal tissues are mediated primarily by nuclear hormone receptors. A cell surface receptor for the hormone on integrin αvβ3 is the initiation site for effects on tumor cells. Clinical hypothyroidism m...

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Literature Corpus work: ec1284e0-c87f-5350-8da4-838aad82180c
DOI: 10.1002/j.2040-4603.2016.tb00712.x

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