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Article

Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation

13 Sept 2018

Abstract excerpt

Myostatin (Mstn) is postulated to be a key determinant of muscle loss and cachexia in cancer. However, no experimental evidence supports a role for Mstn in cancer, particularly in regulating the survival and growth of cancer cells. In this study, we showed that the expression of Mstn was significantly increased in different tumor tissues and human cancer cells. Mstn knockdown inhibited the proliferation of cancer...

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PMID: 30241032
DOI: 10.1016/j.redox.2018.09.009

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