Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for Inflammation

1 Jan 2017

Abstract excerpt

Chronic inflammation is a hallmark of cancer cachexia in both patients and preclinical models. Cachexia is prevalent in roughly 80% of cancer patients and accounts for up to 20% of all cancer‐related deaths. Proinflammatory cytokines IL‐6, TNF‐ α , and TGF‐ β have been widely examined for their regulation of cancer cachexia. An established characteristic of cachectic skeletal muscle is a disrupted capacity for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Muscle Physiology and Disorders
Share to Nutrition and Health in Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28785374
DOI: 10.1155/2017/3292087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for InflammationPMID 28785374Read ↗

Mitochondrial dynamics in cancer-induced cachexiaSemantic proximity Read ↗

Cancer-Associated Muscle Wasting—Candidate Mechanisms and Molecular PathwaysSemantic proximity Read ↗

Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia modelSemantic proximity Read ↗

Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour-bearing mice.Semantic proximity Read ↗

Pathophysiological remodeling of the skeletal muscle microenvironment in patients with lung cancerSemantic proximity Read ↗

Dysregulation of mitophagy in carcinogenesis and tumor progression.Semantic proximity Read ↗

Bridging the tumor microenvironment: the pivotal role of cancer-associated fibroblasts in tumor cachexia developmentSemantic proximity Read ↗

Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexiaSemantic proximity Read ↗

Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscleSemantic proximity Read ↗

Pathological features of tissues and cell populations during cancer cachexiaSemantic proximity Read ↗

Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexiaSemantic proximity Read ↗

The Contribution of Tumor Derived Exosomes to Cancer CachexiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.