Article

Role of Paravertebral muscle myostatin upregulation in the development of idiopathic scoliosis

2022-05-25

Abstract excerpt

Paravertebral muscle (PVM) abnormalities play important roles in the pathogenesis of idiopathic scoliosis (IS), and elevated oxidative stress could result in PVM injury in IS patients, but the underlying mechanism of oxidative stress generation is still unclear. Increased apoptosis, impaired myogenesis and elevated oxidative stress were found in primary skeletal muscle mesenchymal progenitor cells (hSM-MPCs), whic...

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Literature Corpus work: 5676acc6-45b2-59e6-b28d-f28d071708f7
DOI: 10.1101/2022.05.23.493176

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