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Article

Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Cloutier Marissa, Harris Clair, Gayen Srimonta, Maclary Emily, Kalantry Sundeep

Abstract excerpt

X-chromosome inactivation is a dosage compensation mechanism that equalizes X-linked gene expression between male and female mammals through the transcriptional silencing of most genes on one of the two X-chromosomes in females. With a few key exceptions, once the X-chromosome is inactivated replicated copies of that X-chromosome are maintained as inactive in all descendant cells. X-inactivation is therefore a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

Share to In Situ Hybridization, Fluorescence

Share to Sequence Analysis, RNA

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Source

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Identifiers

PMID: 30218368
DOI: 10.1007/978-1-4939-8766-5_14
PMCID: PMC6209079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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