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Article

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

Nature - 30 Jul 2009

Kalantry Sundeep, Purushothaman Sonya, Bowen Randall Bryant, Starmer Joshua, Magnuson Terry

Abstract excerpt

XX female mammals undergo transcriptional silencing of most genes on one of their two X chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is an example of epigenetic regulation. Once enacted in individual cells of the early female embryo, XCI is stably transmitted such that most descendant cells maintain silencing of that X chromosome. In...

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Share to Gene Expression Regulation, Developmental
Share to Genes, X-Linked

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to In Situ Hybridization, Fluorescence

Share to Mice, Transgenic

Share to Reverse Transcriptase Polymerase Chain Reaction

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Identifiers

PMID: 19571810
DOI: 10.1038/nature08161
PMCID: PMC2754729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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